Rangers are finding form at just the right time as they welcome the seven-time French champions to Glasgow for what looks set to be an entertaining night at Ibrox. This is the first competitive meeting between the two clubs since the group stage of the 2007/8 Champions League, when Lyon took home all three points via a 3-0 scoreline.
Leicester are yet to find their best form this season and look short of confidence as their Europa League campaign gets under way on Thursday night. The Foxes have lost two of their first four matches in the Premier League, losing 4-1 at West Ham last month and 1-0 at home to Manchester City on Saturday.
West Ham are back in Europe and will be determined to get off to get off to a flying start as they head to Croatia for their opening Europa League match. The Hammers are unbeaten in the Premier League after four matches but now begin the challenge of also competing in Europe, which could stretch their squad.
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Villarreal are slight favourites to reach the Europa League final after beating Arsenal 2-1 at home and are tipped to advance after drawing in London. Former Gunners boss Unai Emery returns to Emirates Stadium with a strong unit packed full of experienced performers well equipped to cope with pressure.
Roma are unlikely to turn around their Europa League semi-final tie with Man Utd but can at least salvage some pride at Olimpico. The Giallorossi are unbeaten in the Italian capital in this competition and can also boast a good record here in Serie A, so look a value bet to at least win the second leg.